Bioreactors Perfusion Vascular Custom

Flow Bioreactor: the TEB1000 Master Unit

Master Unit TEB1000 Tissue Engineering bioreactor
Culture media flow pumping
Temperature control
CO2 concentration control and
O2 concentration control

The advantage of the EBERS bioreactors with respect to other equipments available in the market resides in the full integration of the components necessary to create the appropriate conditions for cell development.

In this way, none or very few additional equipment is needed to develop the cultures, which results in cleaner, cheaper, easier-to-develop and more effective cultures.

This integration is obtained by means of the TEB1000 Master Unit, the core of the EBERS bioreactors, which integrates all the machinery necessary to generate the appropriate flow conditions for cell including:

  • Culture media flow pumping
  • Temperature control
  • CO2 concentration control and
  • O2 concentration control

Thus, since the appropriate environment for cells is guaranteed by the Master Unit, only a culture chamber, as well simple accessories, like tubing or a medium reservoir, is lacking to the Master Unit to be able to host a Tissue Engineering culture under flow conditions.

This innovative design concept carries a wide number of advantages with respect to other TE bioreactors in the market and allows solving some of the most common problems arising to Tissue Engineering researchers dealing with bioreactors.

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Main advantages of the Master Unit

The fully integrated configuration of TEB1000 Master Unit is able to substitute a large number of equipments frequently used for cell culture in Tissue Engineering, like a CO2 incubators, peristaltic pumps and heaters, since it integrates all their capabilities, allowing a wide variety of experimental set-ups including:

  • Multiple simultaneous experiments
  • Controlled flow profiles for cell stimulation experiments or
  • Experiments under hypoxic conditions

The following table shows the solutions provided by our Master Unit to several frequent problems or demands of Tissue Engineering researchers using bioreactors:

Problem Available market solution Master Unit Advantages
Parallel cultures
  • Expensive equipments
  • General purpose devices
  • Non-customizable culture chambers
  • Multiple pumping systems
  • Customizable culture chambers
  • Up to 25 parallel simultaneous experiments
 Fully customizable culture package system
  • Easily scalable
  • Customizable, flexible and versatile
  • Inexpensive
Bioreactor control Usually carried out by means of
  • External electronic control unit
  • External Computer
 Fully integrated touch screen control No need of external control devices
  • Space saving in your laboratory
  • Inexpensive
Use of additional equipment Controls, actuators, culture chambers and many other complementary gadgets are usually required for growing cells in other bioreactors configuration Apart from the Master Unit, the culture package and the tubing and connectors necessary to complete the culture circuit, no other device is needed to work with EBERS bioreactors. EBERS bioreactors do not require of any additional device to grow cells, which carries
  • Cost saving
  • Use simplicity
Use of a CO2 incubator to get the appropriate conditions for cell development. The need of introducing the bioreactor inside and incubator carries a number of drawbacks as
  • The reduction of the useful space inside the incubator
  • Heat generation due to electrical engines
  • Heat loss due to power wires used to feed the bioreactor
  • Higher contamination risk
 EBERS Master Unit gives all the capabilities of a CO2 incubator No need of a CO2 incubator
  • No heat generation associated to electric engines
  • No heat loss due to bad incubator closing
  • Reduced contamination risk
  • Space saving inside the incubator
  • Cost saving
Determination of the flow profile acting on cell populations A specific purpose software is frequently use to determine the flow profile applied on the cell populations An easy-to-use software is installed in the integrated control, which is controlled by means of a touch screen No need of external software, which implies:
  • No need of software updates
and, in general, removes all the problems associated to the use of a PC to control the equipment.

Please visit the technical specifications sheet for further information of the EBERS TEB1000 Master Unit. The Master Unit system is patent pending.